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Search Results for " coronary artery "

20

Compounds

Cat No. Product Name Synonyms Targets
T9023 Atuliflapon AZD5718 FLAP
Atuliflapon (AZD5718) is a novel 5-Lipoxygenase Activating Protein(FLAP) inhibitor for Treatment of Coronary Artery Disease.
TN6715 7-Ketocholesterol Others
7-Ketocholesterol is a metabolite of Cholesterol
T6033 Zotarolimus ABT-578,A 179578 mTOR
Zotarolimus (ABT-578), an analogue of rapamycin, inhibits FKBP-12 (IC50= 2.8 nM).
T0005 Aspirin Acetylsalicylate,Acetylsalicylic Acid,ASA Mitophagy , Virus Protease , COX , Autophagy
Aspirin (Acetylsalicylic Acid) is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Aspirin is a histone deacetylase inhibitors to up-regulate cel...
T0154 Nebivolol hydrochloride R 065824 hydrochloride,Nebivolol HCl,R-65824 Apoptosis , Adrenergic Receptor
Nebivolol hydrochloride (R 065824 hydrochloride) is a cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE system. It is us...
T1986 Atopaxar E5555,ER-172594-00 Protease-activated Receptor
Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome.
T19345 GP2-114 Others
GP2-114 is a catecholamine exercise mimetic that can be used to study coronary artery disease (CAD).
T1986L Atopaxar Hydrobromide Protease-activated Receptor
Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome.
T8687 Diaminohydroxypropanetetraacetic acid Others
Diaminohydroxypropanetetraacetic acid has been investigated for the treatment of Vascular Disease, Coronary Disease, Myocardial Ischemia, Coronary Restenosis, and Coronary Artery Disease, among others
T24873 TGX-115 TGX 115 PI3K
TGX-115 is a cell-permeable and potent inhibitor of the PI 3-K isoform p110β/p110δ (IC50 values of 0.13 μM for p110β and 0.63 μM for p110δ), an enzyme that regulates platelet adhesion and inhibits phosphoinositide (PI) 3...
T2480 Apabetalone RVX-208,RVX000222 Epigenetic Reader Domain , HIV Protease
Apabetalone (RVX000222) , an effective BET bromodomain inhibitor, has been investigated for the treatment of diabetes, atherosclerosis, and coronary artery disease.
T22787 FPL 55712 LTR
FPL 55712 is a leukotriene receptor and SRS-A antagonist that inhibits bronchoconstriction and can be used in studies of asthma and coronary artery thrombosis.
T10595 BQ-788 BQ788 Endothelin Receptor
BQ-788 is a selective and potent ETB receptor antagonist with potential hypertensive activity.BQ-788 inhibits ET-1 binding to ETB receptors and inhibits exogenous ET-1-induced elevation of coronary artery perfusion press...
T32155 Indecainide Ricainide,Ricainid,Decabid,Indecainidum,Indecainida Others
Indecainide (Ricainid) is a novel antiarrhythmic compound that is carcinogenic and can be used to study chronic stable ventricular arrhythmias secondary to coronary artery disease or cardiomyopathy.
T4179 Probucol disuccinate LDL
Probucol is an anti-hyperlipidemic drug initially developed in the treatment of coronary artery disease by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.
T10364 Arbutamine GP 21213 Adrenergic Receptor
Arbutamine (GP 21213) is a novel potent non-selective beta-adrenoceptor agonist with alpha-1-sympathomimetic activity.Arbutamine promotes cardiac stress and increases heart rate, cardiac contractility.Arbutamine can be u...
T4287 Succinobucol Probucol monosuccinate,AGI-1067 Antioxidant , Reactive Oxygen Species
Succinobucol (Probucol monosuccinate) is a novel phenolic antioxidant small molecule with anti-oxidant and anti-inflammatory properties. It designed to treat atherosclerosis of the blood vessels of the heart or coronary ...
T61028 Mitiperstat AZD4831 Glutathione Peroxidase
Mitiperstat is a potent myeloperoxidase (MPO) inhibitor that is effective in preventing cardiovascular diseases such as heart failure and coronary artery disease.
S00015 Tea polyphenol Apoptosis , Others , Autophagy
Tea polyphenol, also called green tea extract, are a mixture of chemical compounds, such as flavanoids and tannins, found naturally in tea. Polyphenols are powerful antioxidants, which can reduce the risk of developing c...
T31992 Granotapide CETP
Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic syndrome, obesity, diabetes mellitus, prediabetes mellitus, an...
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